Valuing Knowledge: a Reply to the Epistemological Perspective on the Value of Gain-of-Function Experiments
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چکیده
منابع مشابه
Valuing Knowledge: a Reply to the Epistemological Perspective on the Value of Gain-of-Function Experiments
The central ethical claim of Casadevall et al. in “An Epistemological Perspective on the Value of Gain-of-Function Experiments Involving Pathogens with Pandemic Potential” (1) is that, when conducting risk-benefit analyses on studies that use gain-offunction (GOF) methods to create potential pandemic pathogens (PPP), we ought to explicitly account for the value of the “epistemic gains” of the e...
متن کاملReply to “Valuing Knowledge: a Reply to the Epistemological Perspective on the Value of Gain-of-Function Experiments”
We thank Dr. Evans for his letter (1). In reading his letter, it was difficult for us to sort out exactly what his criticism is of our editorial. However, we were able to discern three critical themes: (i) that we are guilty of “double counting” in the sense of counting both the benefits to human health from the knowledge gained via gain-of-function experiments on pathogens with pandemic potent...
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15 صفحه اولAn Epistemological Perspective on the Value of Gain-of-Function Experiments Involving Pathogens with Pandemic Potential
In recent years, scientists have engaged in a vigorous debate regarding the value of so-called gain-of-function (GOF) experiments involving highly pathogenic avian influenza virus (HPAIV) and other pathogens with pandemic potential (PPP). Of particular concern have been experiments whereby something is done to PPP, such as HPAIV, and the pathogen acquires a new property, or GOF, that makes the ...
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ژورنال
عنوان ژورنال: mBio
سال: 2014
ISSN: 2161-2129,2150-7511
DOI: 10.1128/mbio.01993-14